Uniform Biological Material Transfer Agreement – MTA

Definitions

1. PROVIDER: Organization providing the ORIGINAL MATERIAL. The name and address of this party will be specified in an implementing letter.
2. PROVIDER SCIENTIST: The name and address of this party will be specified in an implementing letter.
3. RECIPIENT: Organization receiving the ORIGINAL MATERIAL. The name and address of this party will be specified in an implementing letter.
4. RECIPIENT SCIENTIST: The name and address of this party will be specified in an implementing letter.
5. ORIGINAL MATERIAL: The description of the material being transferred will be specified in an implementing letter.
6. MATERIAL: ORIGINAL MATERIAL, and PROGENY. The MATERIAL shall not include: (a) MODIFICATIONS, or (b) other substances created by the RECIPIENT through the use of the MATERIAL which are not MODIFICATIONS, PROGENY, or UNMODIFIED DERIVATIVES.
7. PROGENY: Unmodified descendant from the MATERIAL, such as virus from virus, cell from cell, or organism from organism, DNA/RNA duplicated by DNA/RNA supplied by the PROVIDER, purified or fractionated subsets of the ORIGINAL MATERIAL.
8. UNMODIFIED DERIVATIVES: Substances created by the RECIPIENT which constitute an unmodified functional subunit or product expressed by the ORIGINAL MATERIAL. Some examples include: proteins expressed by DNA/RNA supplied by the PROVIDER, or monoclonal antibodies secreted by a hybridoma cell line.
9. MODIFICATIONS: Substances created by the RECIPIENT which contain/incorporate the MATERIAL, and UNMODIFIED DERIVATIVES.
10. COMMERCIAL PURPOSES: The sale, lease, license, or other transfer of the MATERIAL or MODIFICATIONS to a for-profit organization. COMMERCIAL PURPOSES shall also include uses of the MATERIAL or MODIFICATIONS by any organization, including RECIPIENT, to perform contract research, to screen compound libraries, to produce or manufacture products for general sale, or to conduct research activities that result in any sale, lease, license, or transfer of the MATERIAL or MODIFICATIONS to a for-profit organization. However, industrially sponsored academic research shall not be considered a use of the MATERIAL or MODIFICATIONS for COMMERCIAL PURPOSES per se, unless any of the above conditions of this definition are met.
11. NONPROFIT ORGANIZATION(S): A university or other institution of higher education or an organization any nonprofit scientific or educational organization qualified under a nonprofit organization statute. As used herein, the term also includes government agencies.

Terms and Conditions of this Agreement

1. The PROVIDER retains ownership of the MATERIAL, including any MATERIAL contained or incorporated in MODIFICATIONS.

2. The RECIPIENT retains ownership of: (a) MODIFICATIONS (except that, the PROVIDER retains ownership rights to the MATERIAL included therein), and (b) those substances created through the use of the MATERIAL or MODIFICATIONS, but which are not PROGENY, UNMODIFIED DERIVATIVES or MODIFICATIONS (i.e., do not contain the ORIGINAL MATERIAL, PROGENY, UNMODIFIED DERIVATIVES). If either 2 (a) or 2 (b) results from the collaborative efforts of the PROVIDER and the RECIPIENT, joint ownership may be negotiated.

a) is to be used solely for teaching and academic research purposes;
b) will not be used in human subjects, in clinical trials, or for diagnostic purposes involving human subjects without the written consent of the PROVIDER;
c) is to be used only at the RECIPIENT organization and only in the RECIPIENT SCIENTIST's laboratory under the direction of the RECIPIENT SCIENTIST or others working under his/her direct supervision;
d) will not be transferred to anyone else outside the RECIPIENT organization without the prior written consent of the PROVIDER.

4. The RECIPIENT and the RECIPIENT SCIENTIST agree to refer to the PROVIDER any request for the MATERIAL from anyone other than those persons working under the RECIPIENT SCIENTIST's direct supervision. To the extent supplies are available, the PROVIDER or the PROVIDER SCIENTIST agrees to make the MATERIAL available, under a separate implementing letter to this Agreement or other agreement having terms consistent with the terms of this Agreement, to other scientists (at least those at NONPROFIT ORGANIZATION(S)) who wish to replicate the RECIPIENT SCIENTIST's research; provided that such other scientists reimburse the PROVIDER for any costs relating to the preparation and distribution of the MATERIAL.

a) The PROVIDER and/or the PROVIDER SCIENTIST shall have the right, without restriction, to distribute substances created by the PROVIDER through the use of the ORIGINAL MATERIAL only if those substances are not PROGENY, UNMODIFIED DERIVATIVES, or MODIFICATIONS.
b) Under a separate implementing letter to this Agreement (or an agreement at least as protective of the PROVIDER's rights), the RECIPIENT and/or the RECIPIENT SCIENTIST may distribute substances created by the RECIPIENT through the use of the ORIGINAL MATERIAL only if those substances are not PROGENY, UNMODIFIED DERIVATIVES, or MODIFICATIONS.
c) The PROVIDER and/or the PROVIDER SCIENTIST shall have the right, without restriction, to distribute MODIFICATIONS to NONPROFIT ORGANIZATION(S) for research and teaching purposes only.
d) The PROVIDER and/or the PROVIDER SCIENTIST shall have the right, without restriction, to distribute MATERIAL for COMMERCIAL PURPOSES. It is recognized by the PROVIDER that such COMMERCIAL PURPOSES may NOT require a commercial license from the RECIPIENT and the RECIPIENT has no obligation to grant a commercial license to its ownership interest in the MATERIAL. Nothing in this paragraph, however, shall prevent the PROVIDER from granting commercial licenses under the PROVIDER's intellectual property rights claiming such MATERIAL, or methods of their manufacture or their use.
e) The RECIPIENT and/or the RECIPIENT SCIENTIST shall have the right, without restriction, to distribute MODIFICATIONS for COMMERCIAL PURPOSES. It is recognized by the RECIPIENT that such COMMERCIAL PURPOSES may NOT require a commercial license from the PROVIDER and the PROVIDER has no obligation to grant a commercial license to its ownership interest in the MATERIAL incorporated in the MODIFICATIONS. Nothing in this paragraph, however, shall prevent the RECIPIENT from granting commercial licenses under the RECIPIENT's intellectual property rights claiming such MODIFICATIONS, or methods of their manufacture or their use.

6. The RECIPIENT acknowledges that the MATERIAL is or may be the subject of a patent application. Except as provided in this Agreement, no express or implied licenses or other rights are provided to the RECIPIENT under any patents, patent applications, trade secrets or other proprietary rights of the PROVIDER, including any altered forms of the MATERIAL made by the PROVIDER. In particular, no express or implied licenses or other rights are provided to use the MATERIAL, MODIFICATIONS, or any related patents of the PROVIDER for COMMERCIAL PURPOSES.

7. If the RECIPIENT desires to use or license the MATERIAL for COMMERCIAL PURPOSES, the RECIPIENT agrees, in advance of such use, to negotiate in good faith with the PROVIDER to establish the terms of a commercial license. It is understood by the RECIPIENT that the PROVIDER shall have no obligation to grant such a license to the RECIPIENT, and may grant exclusive or non-exclusive commercial licenses to others, or sell or assign all or part of the rights in the MATERIAL to any third party(ies), subject to any pre-existing rights held by others and obligations to the Federal Government.

8. If the PROVIDER desires to use or license the MODIFICATIONS for COMMERCIAL PURPOSES, the PROVIDER agrees, in advance of such use, to negotiate in good faith with the RECIPIENT to establish the terms of a commercial license. It is understood by the PROVIDER that the RECIPIENT shall have no obligation to grant such a license to the PROVIDER, and may grant exclusive or non-exclusive commercial licenses to others, or sell or assign all or part of the rights in the MODIFICATIONS to any third party(ies), subject to any pre-existing rights held by others and obligations to theGovernment.

9. The PROVIDER is free to file patent application(s) claiming inventions made by the PROVIDER through the use of the MODIFICATIONS but agrees to notify the RECIPIENT upon filing a patent application claiming MATERIAL or method(s) of manufacture or use(s) of the MATERIAL.

10. The RECIPIENT is free to file patent application(s) claiming inventions made by the RECIPIENT through the use of the MATERIAL but agrees to notify the PROVIDER upon filing a patent application claiming MODIFICATIONS or method(s) of manufacture or use(s) of the MATERIAL.

11. Any MATERIAL delivered pursuant to this Agreement is understood to be experimental in nature and may have hazardous properties. The PROVIDER MAKES NO REPRESENTATIONS AND EXTENDS NO WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED. THERE ARE NO EXPRESS OR IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR THAT THE USE OF THE MATERIAL WILL NOT INFRINGE ANY PATENT, COPYRIGHT, TRADEMARK, OR OTHER PROPRIETARY RIGHTS.

12. Except to the extent prohibited by law, the RECIPIENT assumes all liability for damages which may arise from its use, storage or disposal of the MATERIAL. The PROVIDER will not be liable to the RECIPIENT for any loss, claim or demand made by the RECIPIENT, or made against the RECIPIENT by any other party, due to or arising from the use of the MATERIAL by the RECIPIENT, except to the extent permitted by law when caused by the gross negligence or willful misconduct of the PROVIDER.

13. This agreement shall not be interpreted to prevent or delay publication of research findings resulting from the use of the MATERIAL or the MODIFICATIONS. The PROVIDER SCIENTIST agrees to provide appropriate acknowledgment of the source of the MODIFICATIONS in all publications. The RECIPIENT SCIENTIST agrees to provide appropriate acknowledgment of the source of the MATERIAL in all publications.

14. The PROVIDER agrees to use the MODIFICATIONS in compliance with all applicable statutes and regulations, including Public Health Service and National Institutes of Health regulations and guidelines such as, for example, those relating to research involving the use of animals or recombinant DNA. The RECIPIENT agrees to use the MATERIAL in compliance with all applicable statutes and regulations, including Public Health Service and National Institutes of Health regulations and guidelines such as, for example, those relating to research involving the use of animals or recombinant DNA.

i) if termination should occur under 15(a), the RECIPIENT shall be bound to the PROVIDER by the least restrictive terms applicable to the MATERIAL obtained from the then-available resources; and
ii) if termination should occur under 15(b) or (d) above, the RECIPIENT will discontinue its use of the MATERIAL and will, upon direction of the PROVIDER, return or destroy any remaining MATERIAL. The RECIPIENT, at its discretion, will also either destroy the MODIFICATIONS or remain bound by the terms of this agreement as they apply to MODIFICATIONS; and
iii) In the event the PROVIDER terminates this Agreement under 15( c) other than for breach of this Agreement or for cause such as an imminent health risk or patent infringement, the PROVIDER will defer the effective date of termination for a period of up to one year, upon request from the RECIPIENT, to permit completion of research in progress. Upon the effective date of termination, or if requested, the deferred effective date of termination, RECIPIENT will discontinue its use of the MATERIAL and will, upon direction of the PROVIDER, return or destroy any remaining MATERIAL. The RECIPIENT, at its discretion, will also either destroy the MODIFICATIONS or remain bound by the terms of this agreement as they apply to MODIFICATIONS.

16.Paragraphs 6, 11 and 12 shall survive termination.

17.The MATERIAL is provided at no cost, or with an optional transmittal fee solely to reimburse the PROVIDER for its preparation and distribution costs. If a fee is requested by the PROVIDER, the amount will be indicated in an implementing letter. Main Text Ends Here.

RECIPIENT: Kangma-Healthcode (Shanghai) Biotech Co. Ltd.
RECIPIENT SCIENTIST: Rongrong Zhan
RECIPIENT ADDRESS: Building 15, Lane 118 Furonghua Road, Shanghai 201321, CHINA
RECIPIENT TEL: 021-58086922
RECIPIENT EMAIL: customer@healthcodon.com

Protocol Specification

提示

阅读并同意隐私协议、MTA和使用条款后进行下一步!

PrAuto His-Monster Protein Auto Purifcation Kit 96 DeepWell Plate (Magnetic Beads)- OurProteinFactory

PrAuto His-Monster Protein Auto Purifcation Kit 96 DeepWell Plate (Magnetic Beads)

Product code

protn_AutoHis32S

81.13

Size

Pruoto AutoPurifier 32 Channel

Pr Auto His-Monster Protein Auto Purification Kit - S

Pr Auto His-Monster Protein Auto Purification Kit - S2

Pr Auto His-Monster Protein Auto Purification Kit - M

Pr Auto His-Monster Protein Auto Purification Kit - M2

Quantity

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Document

PrAuto™ Protein Auto Purifcation Kit

高亲和微米级特异性磁珠介质，全套结合，清洗，洗脱试剂

16独立通道

10分钟快速纯化

纯度高达98％

每组得率0.5-2.5 mg

The PrAuto™ Protein Auto Purifcation Kit uses high-affinity micron-level specific magnetic bead media and a complete set of binding, cleaning, and eluting reagents. The PrAuto™ Protein Auto Purifcation Kit has 16 independent channels, which can be purified quickly within 10 minutes, and the purity is as high as 98%, and the yield per group is 0.5-2.5 mg.

PrAuto™ 世界一流的纯化系统

PrAuto™ First-in-Class System in the World

PrAuto™ His-Monster蛋白自动纯化试剂盒专用于高通量、快速目标蛋白的全自动蛋白质纯化

The PrAuto™ His-Monster Protein Auto Purification Kit is dedicated to high-throughput and fast

automatic protein purification of target proteins.

优质原材料

Quality raw materials

医疗级聚丙烯(PP)制成，符合USPVI，化学稳定性高，可以高温灭菌。锥形圆底孔设计，确保样品最低残留

Made of medical grade polypropylene (PP), conforming to USPVI, with high chemical stability and high

temperature sterilization. The tapered round bottom hole design ensures the lowest residual sample.

高亲和微米磁珠

High affinity micron magnetic beads

广泛适用于带有多Histidine (His6-His12) 标签的目标蛋白纯化

专用Monster Beads™微米磁珠，高效结合目标蛋白

蛋白纯度可达98％，得率每组可达0.5-2.5 mg。

It is widely applicable to the purification of target proteins with multiple Histidine (His6-His12) tags. The dedicated Monster Beads™ micron magnetic beads can efficiently bind the target protein with a purity of 98%, and the yield can reach 0.5-2.5 mg per group.

极其便捷

Extremely convenient

磁棒自动吸附磁珠结合目标蛋白

Magnetic rod automatically adsorbs magnetic beads to bind target protein.

极其高效

Extremely efficient

10分钟内依次完成全套流程，结合、分离、清洗、洗脱

Complete the complete set of processes in order within 10 minutes, combining, separating, cleaning and eluting.

高纯化量

High purification capacity

每次运行可纯化0.5-2.5 mg蛋白质，8-40 mg蛋白质纯化总量

Each run can purify 0.5-2.5 mg of protein and 8-40 mg of total protein.

更高通量

Higher throughput

单次一板可完成16个蛋白同时纯化，解决高通量蛋白纯化难题

A single plate can complete the simultaneous purification of 16 proteins, solving the problem of high-throughput protein

purification.

搭配Pruoto Auto Purifier-32高通量自动蛋白纯化仪纯化后的EGFP蛋白

EGFP protein purified with the Pruoto Auto Purifier-32 high-throughput automatic protein purifier.

高纯度

High purity

世界一流的系统，采用D2P技术。独特的设计，使得纯化效果更均一，更高纯度，更方便

纯化后的蛋白可直接应用于下一步的酶切、鉴定以及疾病诊断等

First-in-Class System in the World. PoWered by D2P technology. Unique Design, the purification effect is more uniform, higher

purity, and more convenient. The purified protein can be directly used in the next step of enzyme digestion, identification and

disease diagnosis Wait.

更高效益

Higher efficiency

配合ProteinFactory 蛋白质工厂体外合成系统，和Pruoto™多通道自动蛋白纯化仪，仅需10分钟，即可完成16-96组目标蛋白的快速、

高效纯化，实现效益最大化

Together with the ProteinFactory protein factory in vitro synthesis system and the Pruoto™ multi-channel automatic protein

purification instrument, it only takes 10 minutes to complete the rapid and efficient purification of 16-96 target proteins to

maximize benefits.

操作流程

Protocol

[1] 打开机器 / Turn on the machine
[2] 撕开试剂盒封膜 / Open the kit
[3] 加入待纯化样品 / Add sample
[4] 放入机器 / Put in the machine
[5] 运行程序 / Run the program
[6] 取出试剂盒 / Take out the kit

打开自动纯化仪

Open front cover of the Pruoto™ AutoPurifier-32.
打开PrAuto™蛋白自动纯化试剂盒的包装盒，撕下密封胶带，准备好试剂盒。

Open the packaging box of PrAuto™ Protein AutoPurification kit, tear off the sealing tape, get the kit ready.
在第1列、第7列通道加入待纯化样品

Add samples to Well#1, #7.
将带有样品的自动纯化试剂盒放入机器

Place auto purification kit with samples into the Pruoto™AutoPurifier-32.
运行纯化程序

Run the program for each different kit
收集第6列、第12列通道纯化好的蛋白质

Collect the purified protein from Well #6, #12.

包装规格

Packing specification

1板装16通道

1 board with 16 channels.

protn_AutoHis16S / M

2板装32通道

2 boards with 32 channels.

protn_AutoHis32S / M

PrAuto™ 蛋白自动纯化试剂盒共有两种包装规格，1板装16通道，2板装32通道，满足不同需求、

PrAuto™ protein automatic purification kit has two packaging specifications, 1 plate with 16 channels, 2

plate with 32 channels, to meet different needs.

基本参数

Basic parameters

产品名称 / Name
产品规格 / Specification
通道数量 / Channels
目标蛋白载量 / Max Protein Capacity
上样量 / Sample Volume
亲和标签 / Affinity Tag
产品编号 / Product Code

PrAuto™ Protein Auto Purification Kit 96 DeepWell Plate (Magnetic Beads)
S / M
16 Channels
0.5 mg (S)，2.5 mg (M)
1 mL (S)，5 mL (M)
His6-His12
protn_AutoHis16S

protn_AutoHis32S

protn_AutoHis16M

protn_AutoHis32M

包装清单

Packing specification

蛋白自动纯化试剂盒 x 1

Protein automatic purification kit x 1

磁棒套 x 2

Magnetic rod cover x 2

说明书 x 1

Manual x 1

注释说明

Annotation

以上页面中的出现的产品图片仅作示意，实物产品效果(包括但不限于外观、颜色、尺寸)可能略有差异，请以实物为准。

实际使用中可能因产品个体差异、使用条件和环境因素不同而略有不同，请以实际使用的情况为准。

由于产品批次和生产供应因素实时变化，为尽可能提供准确的产品信息、规格参数、产品特性，OurProteinFactory.com 可能

实时调整和修订以上页面中的文字表述、图片效果等内容，以求与实际产品性能规格、指数、零部件等信息相匹配。

如遇确有进行上述修改和调整必要的情形，恕不专门通知。

The product pictures appearing on the above page are for illustration only. The actual product effects (including but not limited to appearance, color, size) may be slightly different, please refer to the actual product.

In actual use, there may be slight differences due to individual product differences, use conditions and environmental factors. Please refer to the actual use.

Due to the real-time changes in product batches and production supply factors, in order to provide as accurate product information, specification parameters, and product characteristics as possible, OurProteinFactory.com may adjust and revise the text descriptions, image effects and other content on the above pages in real time to achieve the actual Match product performance specifications, indexes, parts and other information.

If it is indeed necessary to make the above modification and adjustment, no special notice will be given.

FOOT

More ways to contact,Building #12-15, Furonghua Road, Pudong District, Shanghai, China Zip: 200120， please call +1-800-955-3390or+86-400-770-5500Monday to Sunday 0:00-24:00